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4 Prevalence, classification, and mechanisms of action of anabolicandrogenic substances Although a uniform classification of anabolicandrogenic substances (AAS) has not been formally established, in practice a functional division based on chemical structure, pharmacokinetics, and route of administration is commonly applied, as illustrated in Figure 1
Obesity Research: Pre-clinical obesity studies have reported substantial effects on body weight, food intake, and fat mass in animal models, with research attributing the breadth and magnitude of these effects to the combined tri-receptor mechanism particularly the additive contribution of glucagon receptor-driven energy expenditure alongside dual incretin activity
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